段瑞雪
硕士生导师、副教授、湖北省省级人才、江苏省双创博士
专业方向：分析化学
电子邮箱：ruixueduan@hubu.edu.cn
教育与研究经历：
2023/09-现在 湖北大学化学与化工学院 副教授
2021/06-2023/08苏州大学放射医学与防护学院 副教授
2016/09-2021/03 新加坡国立大学化学院 博士后（导师：刘小钢院士）
2013/09-2016/07 华中科技大学化学与化工学院 博士（导师：夏帆教授）
2011/07-2013/08 华中科技大学化学与化工学院夏帆教授课题组 科研助理
2011/07-2012/09 中国科学院化学研究所江雷院士课题组 科研助理
2008/09-2011/07 华南师范大学生物光子研究院 硕士（导师：邢达教授）
2004/09-2008/07山西大学生命科学学院 本科
研究方向：
w 纳米技术和功能纳米探针的开发
w 疾病早期诊断分析
w 肿瘤及肾脏相关疾病治疗
主持科研项目：
国家自然科学基金青年项目（82103057），30万，主持，在研；
代表性论文：
1. Ruixue Duan†*, Yueping Li†, Ruru Zhang, Xuelan Hu, Yi wang, Jianfeng Zeng*, Mingyuan Gao*. Reversing Acute Kidney Injury Through Coordinated Interplay of Anti-inflammation and Iron Supplementation. Adv. Mater., 2023, 35, 2301283.
2. Ruixue Duan†, Yuanyuan Xu†, Xuemei Zeng, Jiahui Xu, Liangliang Liang, Zhenzhen Zhang, Zhimin Wang, Xiaoxiao Jiang,Bengang Xing, Bifeng Liu, Angelo All, Xiaosong Li*, Luke P. Lee* and Xiaogang Liu*. Uncovering the Metabolic Origin of Aspartate for Tumor Growth using an Integrated Molecular Deactivator. Nano Lett., 2021, 21, 778-784.
3. Ruixue Duan†, Zhenyu Zhang†, Fuxin Zheng†, Longwang Wang, Ju Guo, Tianchi Zhang, Xiaomeng Dai, Shengwei Zhang, Dong Yang, Renrui Kuang, Gongxian Wang, Chaohong He,Abdul Hakeem, Chang Shu, Ping Yin, Xiaoding Lou, Fuqing Zeng, Huageng Liang*, and Fan Xia*. Combining protein and miRNA quantification for bladder cancer analysis. ACS Appl. Mater. Inter., 2017, 9, 23420–23427.
4. Yueping Li, Ruixue Duan*. Nanostructures with at least one dimension in ultra-small size for the treatment of acute kidney injury. Giant, 2022, 11, 100111.
5. Ruixue Duan, Xiaolei Zuo, Shutao Wang, Xiyun Quan, Dongliang Chen, Zhifei Chen, Fan Xia* and Lei Jiang. Quadratic isothermal amplification for the detection of microRNA. Nat. protoc., 2014, 9, 597–607.
6. Ruixue Duan, Xiaoding Lou*, Fan Xia*. The development of nanostructure assisted isothermal linear amplification. Chem. Soc. Rev., 2016, 45, 1738-1749.
7. Ruixue Duan, Xiaolei Zuo, Shutao Wang, Xiyun Quan, Dongliang Chen, Zhifei Chen, Fan Xia* and Lei Jiang. Lab in a tube: Ultra-sensitive detection of microRNAs in single cell and breast cancer patients using Quadratic Isothermal Amplification. J. Am. Chem. Soc., 2013, 135, 4604−4607.
8. Ruixue Duan, Fan Xia, and Lei Jiang*. Constructing Tunable Nanopores and Their Application in Drug Delivery. ACS Nano, 2013, 7, 8344-8349.
9. Ruixue Duan†, Boya Wang†, Fan Hong, Tianchi Zhang, Yongmei Jia, Jiayu Huang, Abdul Hakeem, Nannan Liu, Shaofang Xu, Zhifei Chen, Xiaoding Lou and Fan Xia*. Real-Time Monitoring of Enzyme-Free Strand Displacement Cascade by Colorimetric Assays. Nanoscale, 2015,7, 5719-5725.
10. Ruixue Duan, Boya Wang, Tianchi Zhang, Zhenyu Zhang, Shaofang Xu, Zhifei Chen, Xiaoding Lou and Fan Xia*. Sensitive and bidirectional detection of urine telomerase based on the four detection-color states of difunctional gold nanoparticle probe. Anal. Chem., 2014, 86, 9781–9785.
11. Ruixue Duan, Xiaoming Zhou, Da Xing*. Electrochemiluminescence Biobarcode Method Based on Cysteamine-Gold Nanoparticle Conjugates. Anal. Chem., 2010, 82, 3099–3103.
12. Di kang†, Ruixue Duan†, Yerpeng Tan†, Fan Hong, Boya Wang, Zhifei Chen, Shaofang Xu, Xiaoding Lou, Wei Wei, Bernard Yurke and Fan Xia*. Speeding up the self-assembly of DNA nanodevice by a variety of polar solvents. Nanoscale, 2014, 6, 14153-14157.
